Inheritance and testicular cancer

Testicular Cancer and Cryptorchidism

The failure of testicular descent or cryptorchidism is the most common defect in newborn boys. The descent of the testes during development is controlled by insulin-like 3 peptide and steroid hormones produced in testicular Leydig cells, as well as by various genetic and developmental factors. While in some cases the association with genetic abnormalities and environmental causes has been shown...

Testicular cancer

Testicular cancer is cancer that develops in the testicles, a part of the male reproductive system. Although testicular cancer can be derived from any cell type found in the testicles, more than 95% of testicular cancers are germ cell tumors. Most of the remaining 5% are sex cord-gonadal stromal tumors derived from Leydig cells or Sertoli cells. Over man's lifetime, his risk of testicular cance...

[Testicular cancer].

Testicular cancer.

Despite the overall cure rate now in excess of 90%, innovation in management of germ cell tumors continues. The report that 80% of patients with extragonadal germ cell tumors have either carcinoma in situ or atrophic tubules as evidence of tumor rejection emphasizes the need to investigate the testis in patients with undiagnosed primary cancer because even today treatment delay is worsening pro...

Testicular cancer

Testicular cancer is cancer that develops in the testicles, a part of the male reproductive system. Although testicular cancer can be derived from any cell type found in the testicles, more than 95% of testicular cancers are germ cell tumors. Most of the remaining 5% are sex cord-gonadal stromal tumors derived from Leydig cells or Sertoli cells. Over man's lifetime, his risk of testicular cance...